Partelli Stefano Professore AssociatoMedicineMED/18 - MEDS-06/A - Chirurgia Generale

Education:

2004                Degree in Medicine and Surgery, University of Verona, Italy

2008-2009       Research Fellow, Queen Mary University, London, UK.

2010                General Surgery Board Certification, University of Verona Italy

2011-2014      PhD in Surgical Science and Hepatobiliary Pancreatic Diseases University of Verona, Italy

 

Working positions:

2011-2012       Consultant at General Surgery – Sacro Cuore-Don Calabria, Negrar, Italy

2012-2014       Consultant at Pancreatic Surgery – Ospedali Riuniti, Ancona, Italy

From 2015       Consultant at Pancreatic Surgery – IRCCS San Raffaele Hospital, Milan, Italy

From 2018       Assistant Professor of Surgery at Vita-salute San Raffaele University Milan, Italy

 

Research  Activity:

Impact Factor at 24.06.17 based on Journal Citation Report 2017= 511

Author h index: 20

Nr of total citations: 1164

Member of the following scientific societies: Associazione Italiana Studio Pancreas (AISP), European  Neuroendocrine Tumor Society (ENETS), North American Neuroendocrine Tumor Society (NANETS), European Society of  Surgical Oncology (ESSO).

Reviewer: British Journal of Surgery, British Journal of Cancer, BMJ Case Reports, Digestive and Liver Disease, Rivista Tumori.

Invited speaker at 40 national and international meeting 

Awards and prizes (limited to neuroendocrine field):

Oct 2008       Travel Fellowship Grant awarded by the “European Society of Surgical Oncology”

Mar 2011      Selected Best Oral Communication- 8th ENETS Conference Lisbon, Portugal

Oct 2011       Young Investigator Award, Neuroendocrine Tumor Symposium, Minneapolis, US

Mar 2012      Selected Best Oral Communication – 9th ENETS Conference Copenhagen, Denmark

Oct 2014       Travel Grant Prize, Neuroendocrine Tumor Symposium, Nashville, US

Dec 2014       Travel Grant Award, UKI NETS 12th National Conference, London, UK 

Selected publications:

Partelli S, Boninsegna L, Salvia R, Bassi C, Pederzoli P, Falconi M. Middle-preserving pancreatectomy for multicentric body-sparing lesions of the pancreas. Am J Surg. 2009 Sep;198(3):e49-53.

Partelli S, Fernández-Del Castillo C, Bassi C, Mantovani W, Thayer S, Crippa S, Ferrone C, Falconi M, Pederzoli P, Warshaw A, Salvia R  Invasive intraductral papillary mucionous carcinomas of the pancreas: predictors of survival and the role of lymph node ratio. Ann Surg. 2010 Mar;251(3):477-82

Partelli S, Mukherjee S, Mawire K, Hutchins RR, Abraham AT, Bhattacharya S, Kocher HM. Larger hepatic metastases are more frequent with N0 colorectal tumours and are associated with poor prognosis: Implications for surveillance. Int J Surg. 2010 Jun 19.

Boninsegna L, Partelli S, D’Innocenzio MM, Capelli P, Scarpa A, Bassi C, Pederzoli P, Falconi M. Pancreatic Cystic Endocrine Tumors: A Different Morphological Entity Associated with a Less Aggressive Behavior. Neuroendocrinology. 2010 Aug 5.

Bettini R, Partelli S, Boninsegna L, Capelli P, Crippa S, Pederzoli P, Scarpa  A, Falconi M. Tumor size correlates with malignancy in nonfunctioning pancreatic endocrine tumor. Surgery 2011;150:75-82

Butturini G, Partelli S, Crippa S, Malleo G, Rossini R, Casetti L, Melotti GL, Piccoli M, Pederzoli G, Bassi C. Perioperative and long-term outcomes after left pancreatectomy: a single-institution, non-randomized, comparative study between open and laparoscopic approach. Surg Endosc 2011;25:2871-2878

Partelli S, Crippa S, Barugola G, Tamburrino D, Capelli P, D’Onofrio M, Pederzoli P, Falconi M. Splenic artery invasion in pancreatic adenocarcinoma of the body and tail: a novel prognostic parameter for patient selection. Ann Surg Oncol 2011;18:3608-3614

Barugola G, Partelli S, Crippa S, Capelli P, D’Onofrio M, Pederzoli P, Falconi M. Outcomes after resection of locally advanced or borderline resectable pancreatic cancer after neoadjuvant therapy. Am J Surg. 2012;203(3):132-9 Aug 6

Crippa S, Partelli S, Zamboni G, Barugola G, Capelli P, Inama M, Bassi C, Pederzoli P, Falconi M. Poorly differentiated resectable pancreatic cancer: is upfront surgery worthwhile? Surgery 2012;152(3 Suppl 1);S112-9

 

Partelli S, Frulloni L, Minniti C, Bassi C, Barugola G, D’Onofrio M, Crippa S, Falconi M. Faecal elastase-1 is an independent predictor of survival in advanced pancreatic cancer. Dig Liver Dis. 2012 Nov;44(11):945-51.

Partelli S, Crippa S, Capelli P, Neri A, Bassi C, Zamboni G, Barugola G, Falconi M. Adequacy of lymph node retrieval for ampullary cancer and its association with improved staging and survival. World J Surg. 2013 Jun;37(6):1397-404.

Partelli S, Gaujoux S, Boninsegna L, Cherif R, Crippa S, Couvelard A, Scarpa  A, Ruszniewski P, Sauvanet A, Falconi M. Pattern and clinical predictors of lymph node involvement in nonfunctioning pancreatic neuroendocrine tumors (NF-PanNETs). JAMA Surg. 2013 Oct;148(10):932-9.

Arumugam P, Partelli S, Coleman SJ, Cataldo I, Beghelli S, Bassi C, Wijesuriya N, Aleong JA, Froeling FE, Scarpa A, Kocher HM. Ezrin expression is an independent prognostic factor in gastro-intestinal cancers. J Gastrointest Surg.  2013 Dec;17(12):2082-91.

Gaujoux S, Partelli S, Maire F, D’Onofrio M, Larroque B, Tamburrino D, Sauvanet A, Falconi M, Ruszniewski P. Observational study of natural history of small sporadic nonfunctioning pancreatic neuroendocrine tumors. J Clin Endocrinol Metab. 2013 Dec;98(12):4784-9.

Barugola G, Partelli S, Crippa S, Butturini G, Salvia R, Sartori N, Bassi C,  Falconi M, Pederzoli P. Time trends in the treatment and prognosis of resectable  pancreatic cancer in a large tertiary referral centre. HPB (Oxford). 2013 Dec;15(12):958-64.

Partelli S, Tamburrino D, Crippa S, Facci E, Zardini C, Falconi M. Evaluation of a predictive model for pancreatic fistula based on amylase value in drains after pancreatic resection. Am J Surg. 2014 Oct;208(4):634-9.

Partelli S, Rinzivillo M, Maurizi A, Panzuto F, Salgarello M, Polenta V, Delle Fave G, Falconi M. The Role of Combined Ga-DOTATOC and (18)FDG PET/CT in the Management of Patients with Pancreatic Neuroendocrine Tumors. Neuroendocrinology. 2014 Oct 3.

Partelli S, Inama M, Rinke A, Begum N, Valente R, Fendrich V, Tamburrino D, Keck T, Caplin ME, Bartsch D, Thirlwell C, Fusai G, Falconi M. Long-Term Outcomes of Surgical Management of Pancreatic Neuroendocrine Tumors with Synchronous Liver Metastases. Neuroendocrinology. 2015;102(1-2):68-76. doi: 10.1159/000431379. Epub 2015 May 29.

Partelli S, Tamburrino D, Lopez C, Albers M, Milanetto AC, Pasquali C, Manzoni M, Toumpanakis C, Fusai G, Bartsch D, Falconi M. Active Surveillance versus Surgery of Nonfunctioning Pancreatic Neuroendocrine Neoplasms ≤2 cm in MEN1 Patients. Neuroendocrinology. 2016;103(6):779-86. doi: 10.1159/000443613

Partelli S, Crippa S, Castagnani R, Ruffo G, Marmorale C, Franconi AM, De Angelis C, Falconi M. Evaluation of an enhanced recovery protocol after

pancreaticoduodenectomy in elderly patients. HPB (Oxford). 2016 Feb;18(2):153-8.

doi: 10.1016/j.hpb.2015.09.009.

Crippa S, Partelli S, Bassi C, Berardi R, Capelli P, Scarpa A, Zamboni G, Falconi M. Long-term outcomes and prognostic factors in neuroendocrine carcinomas of the pancreas: Morphology matters. Surgery. 2016 Mar;159(3):862-71. doi:10.1016/j.surg.2015.09.012.

Partelli S, Barugola G, Sartori A, Crippa S, Falconi M, Ruffo G. Single-incision laparoscopic cholecystectomy versus traditional laparoscopic cholecystectomy performed by a single surgeon: findings of a randomized trial. Surg Today. 2016 Mar;46(3):313-8. doi: 10.1007/s00595-015-1182-7.

Partelli S, Cirocchi R, Randolph J, Parisi A, Coratti A, Falconi M. A systematic review and meta-analysis of spleen-preserving distal pancreatectomy with preservation or ligation of the splenic artery and vein. Surgeon. 2016 Apr;14(2):109-18. doi: 10.1016/j.surge.2015.11.002.

Falletta S, Partelli S, Rubini C, Nann D, Doria A, Marinoni I, Polenta V, Di Pasquale C, Degli Uberti E, Perren A, Falconi M, Zatelli MC. mTOR inhibitors response and mTOR pathway in pancreatic neuroendocrine tumors. Endocr Relat Cancer. 2016 Nov;23(11):883-891.

Partelli S, Cirocchi R, Crippa S, Cardinali L, Fendrich V, Bartsch DK, Falconi M. Systematic review of active surveillance versus surgical management of asymptomatic small non-functioning pancreatic neuroendocrine neoplasms. Br J Surg. 2017 Jan;104(1):34-41. doi: 10.1002/bjs.10312.

Genç CG, Jilesen AP, Partelli S, Falconi M, Muffatti F, van Kemenade FJ, van  Eeden S, Verheij J, van Dieren S, van Eijck CHJ, Nieveen van Dijkum EJM. A New Scoring System to Predict Recurrent Disease in Grade 1 and 2 Nonfunctional Pancreatic Neuroendocrine Tumors. Ann Surg. 2017 Jan 3. doi: 10.1097/SLA.0000000000002123. [Epub ahead of print]

Falconi M, Partelli S. Neuroendocrine tumours in 2016: Defining rules for increasingly personalized treatments. Nat Rev Clin Oncol. 2017 Feb;14(2):80-82. doi: 10.1038/nrclinonc.2016.197.

Partelli S, Bartsch DK, Capdevila J, Chen J, Knigge U, Niederle B, Nieveen van Dijkum EJ, Pape UF, Pascher A, Ramage J, Reed N, Ruszniewski P, Scoazec JY, Toumpanakis C, Kianmanesh R, Falconi M; all other Antibes Consensus Conference participants. ENETS Consensus Guidelines for Standard of Care in Neuroendocrine Tumours: Surgery for Small Intestinal and Pancreatic Neuroendocrine Tumours. Neuroendocrinology. 2017 Feb 25. doi: 10.1159/000464292.

Scarpa A, Chang DK, Nones K, Corbo V, Patch AM, Bailey P, Lawlor RT, Johns AL, Miller DK, Mafficini A, Rusev B, Scardoni M, Antonello D, Barbi S, Sikora KO, Cingarlini S, Vicentini C, McKay S, Quinn MC, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, McLean S, Nourse C, Nourbakhsh E, Wilson PJ, Anderson MJ, Fink JL, Newell F, Waddell N, Holmes O, Kazakoff SH, Leonard C, Wood S, Xu Q, Nagaraj SH,  Amato E, Dalai I, Bersani S, Cataldo I, Dei Tos AP, Capelli P, Davì MV, Landoni L, Malpaga A, Miotto M, Whitehall VL, Leggett BA, Harris JL, Harris J, Jones MD,  Humphris J, Chantrill LA, Chin V, Nagrial AM, Pajic M, Scarlett CJ, Pinho A, Rooman I, Toon C, Wu J, Pinese M, Cowley M, Barbour A, Mawson A, Humphrey ES, Colvin EK, Chou A, Lovell JA, Jamieson NB, Duthie F, Gingras MC, Fisher WE, Dagg  RA, Lau LM, Lee M, Pickett HA, Reddel RR, Samra JS, Kench JG, Merrett ND, Epari K, Nguyen NQ, Zeps N, Falconi M, Simbolo M, Butturini G, Van Buren G, Partelli S, Fassan M; Australian Pancreatic Cancer Genome Initiative, Khanna KK, Gill AJ, Wheeler DA, Gibbs RA, Musgrove EA, Bassi C, Tortora G, Pederzoli P, Pearson JV, Waddell N, Biankin AV, Grimmond SM. Whole-genome landscape of pancreatic neuroendocrine tumours. Nature. 2017 Mar 2;543(7643):65-71. doi:10.1038/nature21063.

Partelli S, Pecorelli N, Muffatti F, Belfiori G, Crippa S, Piazzai F, Castoldi R, Marmorale C, Balzano G, Falconi M. Early Postoperative Prediction of Clinically Relevant Pancreatic Fistula after Pancreaticoduodenectomy: usefulness of C-reactive Protein. HPB (Oxford). 2017 Apr 6. pii: S1365-182X(17)30527-0. doi:10.1016/j.hpb.2017.03.001.

Panzuto F, Cicchese N, Partelli S, Rinzivillo M, Capurso G, Merola E, Manzoni M, Pucci E, Iannicelli E, Pilozzi E, Rossi M, Doglioni C, Falconi M, Delle Fave G. Impact of Ki67 re-assessment at time of disease progression in patients with pancreatic neuroendocrine neoplasms. PLoS One. 2017 Jun 23;12(6):e0179445. doi:10.1371/journal.pone.0179445.

Partelli S, Cirocchi R, Rancoita PMV, Muffatti F, Andreasi V, Crippa S, Tamburrino D, Falconi M. A. Systematic review and meta-analysis on the role of palliative primary resection for pancreatic neuroendocrine neoplasm with liver metastases. HPB (Oxford). 2017 Nov 29. pii: S1365 182X(17)31127-9. doi:10.1016/j.hpb.2017.10.014. [Epub ahead of print] Review. PubMed PMID: 29196022

Partelli S, Bertani E, Bartolomei M, Perali C, Muffatti F, Grana CM, Schiavo Lena M, Doglioni C, Crippa S, Fazio N, Zamboni G, Falconi M. Peptide receptor radionuclide therapy as neoadjuvant therapy for resectable or potentially resectable pancreatic neuroendocrine neoplasms. Surgery. 2017 Dec 25. pii:S0039-6060(17)30827-9. doi: 10.1016/j.surg.2017.11.007. [Epub ahead of print] PubMed PMID: 29284590.